Dr Laurent Deslandes, CR1 CNRS, group leader
Laurent did his PhD at the LIPM in Dominique Roby and Yves Marco’s lab where he studied the genetic determinism of Arabidopsis resistance to Ralstonia solanacearum. His work led to the cloning of RRS1-R, a resistance gene encoding for an atypical TIR-NBS-LRR-WRKY protein that confers a broad spectrum resistance towards this pathogenic bacteria. He spent 2 years in Cologne, at the Max-Planck Institut where he focused on the identification of interacting partners of WRKY transcription factors. He was recruited as a research scientist at CNRS (Centre National de la Recherche Scientifique) and moved back to Toulouse (LIPM) to work on the identification and the characterization of a resistance perception complex that involves RRS1-R and its matching avirulence protein from Rasltonia, PopP2. Recently, his work revealed that PopP2 displays an autoacetyl-transferase activity that targets a lysine residue required for the activation of the RRS1-R immune response. He is now focusing on the Identification of host proteins targeted by PopP2 activity and/or involved in the regulation of its enzymatic activity. This work should bring new clues on the molecular role(s) played by protein acetylation during plant innate immunity.
Dr Domique Tremousaygue, CR1 CNRS
Dominique joined the Dominique Roby and Yves Marco group in 2007. She previously spent some years studying transcriptional regulations on the model plant Arabidopsis thaliana, focusing first on mechanisms underlying regulation of translation initiation and then on the role of TCP transcription factors. She has been involved in the Arabidopsis genome and ESTs sequencing projects. Now she is working on transcriptional regulations involving RRS1 proteins. She is also interested in natural variations at the RRS1 gene locus, related to resistance or susceptibility in Arabidopsis.
Dr Richard Berthomé, CR INRA
I started my scientific career in the Cellular biology laboratory at INRA (Versailles center), working in the Mark Tepfer’s team during my PhD and in the Hervé Vaucheret’s group during my first-post-doc. During these periods, my projects aimed at studying mechanisms by which plants suppress the expression of genes introduced by transgenesis or resist to viruses through gene silencing. My second post-doc, realized in the J.Traas’s group (Cellular Biology laboratory at INRA, Versailles) and in the Dirk Inzé's laboratory (VIB, Gend, Belgium) aimed at studying the role of the cell cycle in the shoot apical meristem organization control. I was then recruited as CR2 in 2001 at the Genetic and Plant Breeding unit (IJPB-INRA, Versailles) in the " Organites and Reproduction” team. The project developed was dedicated to study the involvement of mitochondria in plant development and more particularly in sexual reproduction. In 2007, I joined the functional Genomic of Arabidopsis group of the Plant Genomics Research Unit (INRA-EVRY). My work mainly focused on i) the study of the plant genome expression regulation in fluctuating environments, more particularly in response to abiotic stresses (cell differentiation process, nitrogen starvation, salt stress, organic pollutant) and ii) in the study of the pyrimidines salvage pathway and its engineering to develop a new method allowing tissue specific RNA labeling and transcriptome analysis. In October, 2012, I joined the DRYM team at the Plants Microorganisms Interaction laboratory (LIPM). Currently, I develop a new project aimed at deciphering and modelize the modulation of the plant immune response in abiotic stress conditions. More particularly, this project focuses on the study of the mechanisms which underlie the modification of plant defense response to the bacteria Ralstonia solanacearum at higher temperatures.
Patrick Dabos, INRA technician
Patrick has worked since 1984 at the LIPM. He is currently mainly involved in the project concerning the natural variations at the RRS1 gene locus and the plant response to Ralstonia. He is also member of the Health and Safety Committee of the laboratory.